Ionis Pharmaceuticals, Inc. (IONS) FY2026 YTD Q2 Statement of Cash Flows
2026-01-01 to 2026-06-30
Statement of Cash Flows
2026-01-01 to 2026-06-30
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Chart details
Ionis Pharmaceuticals, Inc. cash flow reconciliation, Jan 1, 2026 through Jun 30, 2026
Cash flows for Jan 1, 2026 through Jun 30, 2026. Cash basis: Cash, cash equivalents, and restricted cash. Beginning cash: Dec 31, 2025. Ending cash: Jun 30, 2026. Beginning and ending cash are dated balances. Positive cash flows add cash; negative cash flows reduce it.
- Beginning cash on Dec 31, 2025
- 372,260,000 US dollars. Beginning cash: Cash, cash equivalents, and restricted cash
- Operating activities
- negative 227,288,000 US dollars. Net cash used.
- Net loss
- negative 207,174,000 US dollars
- Depreciation
- 6,734,000 US dollars
- Amortization of right-of-use operating lease assets
- 6,990,000 US dollars
- Amortization of other assets
- 1,361,000 US dollars
- Amortization of debt issuance costs
- 4,150,000 US dollars
- Non-cash interest related to sale of future royalties
- 34,538,000 US dollars
- Stock-based compensation expense
- 88,870,000 US dollars
- Non-cash losses related to other assets
- 481,000 US dollars
- Accounts payable
- 18,583,000 US dollars
- Income taxes
- 164,000 US dollars
- Accrued compensation
- negative 65,943,000 US dollars
- Accrued liabilities and other liabilities
- 12,851,000 US dollars
- Deferred contract revenue
- negative 28,895,000 US dollars
- Amortization of discount on investments, net
- negative 9,533,000 US dollars
- Non-cash royalty revenue related to sale of royalties
- negative 22,387,000 US dollars
- Loss (gain) on investments, net
- negative 12,401,000 US dollars
- Contracts receivable
- 7,214,000 US dollars
- Inventories
- negative 24,626,000 US dollars
- Other current and long-term assets
- negative 38,265,000 US dollars
- Investing activities
- 560,317,000 US dollars. Net cash provided.
- Proceeds from sale of short-term investments
- 1,114,805,000 US dollars
- Purchases of short-term investments
- negative 513,005,000 US dollars
- Purchases of property, plant and equipment
- negative 37,843,000 US dollars
- Acquisition of licenses and other assets, net
- negative 3,640,000 US dollars
- Financing activities
- negative 355,036,000 US dollars. Net cash used.
- Proceeds from issuance of common stock through equity plans, net
- 77,560,000 US dollars
- Repayment of 0 percent convertible senior notes due 2026
- negative 432,511,000 US dollars
- Principal payments on mortgage debt
- negative 85,000 US dollars
- Operating adjustment reconciliation
- 409,224,000 US dollars. Intermediate calculation joining the operating reconciliation branches. Its gross amount includes any portion of net income routed through this junction. It is not an additional cash source or use.
- financing gross reconciliation
- 432,596,000 US dollars. Gross amount at the activity's junction before offsetting its receipts and deductions. It is not an additional cash source or use.
- investing gross reconciliation
- 1,114,805,000 US dollars. Gross amount at the activity's junction before offsetting its receipts and deductions. It is not an additional cash source or use.
- Exchange-rate effect
- negative 188,000 US dollars
- Ending cash on Jun 30, 2026
- 350,065,000 US dollars. Ending cash: Cash, cash equivalents, and restricted cash
- Cash sources and uses
- 932,577,000 US dollars. Opening cash plus net sources, equal to net uses plus ending cash.
- Net cash change
- negative 22,195,000 US dollars. Ending cash minus beginning cash.
- Cash flow / Net income
- Not meaningful. Operating cash flow divided by reconciliation net income for the same period. The ratio is not meaningful when net income is zero or negative.
- Operating cash flow
- negative 227,288,000 US dollars. Operating cash flow used in the free cash flow calculation.
- Cash purchases of property, plant and equipment
- 37,843,000 US dollars. These cash purchases are already included in investing activities above.
- Free cash flow
- negative 265,131,000 US dollars. A supplemental measure; finance-lease payments are excluded from this definition.
Chart connections
- Beginning cash plus operating, investing and financing cash flows plus the exchange-rate effect equals ending cash. Negative amounts reduce cash.
- Financing contributions meet at a reconciliation junction before connecting to the net cash total.
- Investing contributions meet at a reconciliation junction before connecting to the net cash total.
- Operating reconciliation adjustments are not all independent cash receipts.
- Net loss −$207.17M − net operating adjustments $20.11M = operating cash −$227.29M. The loss reduces the earnings basis of the reconciliation; it is not a cash payment. The signed loss remains a deduction at the operating reconciliation junction.
- Each activity has one net cash bar connected to the shared cash pool. Positive activity totals enter the pool; negative activity totals leave the pool to fund that activity's net payments. The central pool does not assign a particular funding source to a particular payment.
- The intermediate calculation bars include both sides of the displayed activity breakdowns; they are not additional cash flows.
- Operating cash flow minus cash purchases of property, plant and equipment equals free cash flow: negative 227,288,000 US dollars minus 37,843,000 US dollars equals negative 265,131,000 US dollars.
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